
Case Study
How a Project Management Office Accelerated Delivery by 124%
Business Sector: MedTech
A fast-growing medtech innovator needed operational discipline to match its groundbreaking science. With MustardSeed as a partner, the company built a fully integrated Project Management Office (PMO) from the ground up. The new PMO introduced portfolio-wide risk governance, resource planning, and real-time forecasting, creating structure without slowing innovation.
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Before vs. After: Transformation at a Glance
- From untracked tasks → 76% milestone completion in 4 months
- From siloed teams → unified resourcing with 35 scientists as “one team”
- From anecdotal risks → portfolio dashboards covering 100% of active programs
- From decision churn → operating reviews streamlined by 80%
The Challenge: Innovation Outpacing Execution
As the company grew, execution gaps started to compound:
- Untracked tasks & weak accountability meant commitments slipped.
- Critical path milestones weren’t understood or escalated to leadership.
- Resources were overallocated, but leaders lacked proof to rebalance workloads.
- Risks were casually discussed but never centrally tracked or mitigated.
- No formal PMO existed; ad hoc project management was unsustainable.
For years, subject-matter experts had been managing projects on top of their day jobs. As pipelines expanded, this model became unsustainable. Leadership recognized the need for a centralized PMO to provide clarity, structure, and governance (before growth outpaced control).
The Solution: A Scalable PMO, Built from Scratch
PMO Infrastructure & Program Management
- Deployed dedicated PMs across all NPIs and sustaining programs
- Built Integrated Master Schedules (IMS) with baselines and dependencies
- Standardized operating reviews, cutting prep time by 80%
Risk & Resource Governance
- Delivered portfolio-wide risk dashboards
- Centralized resource planning using Smartsheet Resource Manager
- Converted siloed teams into a “one-team” model
Leadership, Data Visibility & Decision Enablement
- Rolled out PowerBI dashboards for real-time financials & forecasting
- Introduced Monte Carlo analysis for launch realism
- Enabled confident decision-making with live dashboards
Change Management & Adoption
- Overcame early resistance by embedding PMs directly into teams
- Phased rollout balanced execution with cultural adoption
- Shifted SMEs from ad-hoc project tracking to disciplined risk, schedule, and resource management
- Built organization-wide trust through consistent wins and transparency

The Impact: Execution Discipline
- Milestone completion jumped from 34% to 76% within 4 months.
- On-time delivery grew from 18% to 53% in the same timeframe.
- Standardized operating reviews cut prep time by 80%, freeing SMEs to focus on execution instead of reporting.
- Meeting efficiency improved through centralized minutes, version control, and automated updates.
- Portfolio-wide risk dashboards gave leadership a single source of truth.
- Smartsheet Resource Manager shifted teams from siloed work to a "one-team" model with clearer capacity planning.
- Monte Carlo schedule risk analysis introduced realistic launch forecasting.
- ELT decision-making accelerated thanks to baseline tracking and integrated scheduling.
Strategic Takeaway
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